nCompound: TB-500 (Thymosin Beta-4 Fragment)
nCAS Number: 77591-33-4
nMolecular Formula: C212H350N56O78S
nPurity: 98.62% (HPLC-UV verified)
nThird-Party Testing: Testides Analytical (independent third-party lab)
nCOA Download: View Full COA (PDF)
nReport: DBAV-TB500-10-051226
nSource: Research grade, third-party tested
nShipping: Same-day shipping from our US facility
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TB-500 peptide: a synthetic version of a 43-amino acid region of Thymosin Beta-4 (TB4), a naturally occurring protein involved in cell migration and differentiation research. Available from Maple Research Labs with greater than 99%+ HPLC-verified purity and third-party COA testing.
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- Sequence Region: Thymosin Beta-4 active fragment
- Molecular Weight: Approximately 4963 Da
- Purity: >99%+ (HPLC verified)
- Form: Lyophilized powder
- Quantity: 10mg per vial
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TB-500 Peptide Research Summary
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TB-500 is a synthetic peptide representing the active region of Thymosin Beta-4, a 43-amino acid protein expressed in virtually all mammalian cell types. It contains the key actin-binding domain (LKKTETQ) responsible for many of the observed biological activities in research settings. Research has focused on TB-500 interaction with globular actin (G-actin), which plays a central role in cytoskeletal dynamics.
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Mechanism of Action Research
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The primary molecular mechanism under investigation involves TB-500 ability to sequester G-actin monomers, thereby regulating actin cytoskeleton dynamics essential for cell migration. Published preclinical studies have examined TB-500 in the context of wound repair models, cardiac tissue research, and inflammatory response modulation in rodent and in vitro systems.
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All published findings referenced here are based on animal models and in vitro systems. No therapeutic claims are made.
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Certificate of Analysis (COA)
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Testing Laboratory: Testides Analytical. Purity (HPLC-UV): 98.62%. Report: DBAV-TB500-10-051226. Download Full COA (PDF)
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For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.
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