nCompound: MOTS-c
nCAS Number: 1627580-64-6
nMolecular Formula: C78H123N23O24S2
nPurity: 99.69% (HPLC-UV verified)
nThird-Party Testing: Testides Analytical (independent third-party lab)
nCOA Download: View Full COA (PDF)
nReport: DBAV-MOTS-10-051226-02
nSource: Research grade, third-party tested
nShipping: Same-day shipping from our US facility
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MOTS-C peptide: a mitochondrial-derived peptide encoded within the 12S rRNA gene of mitochondrial DNA. This research compound is available from Maple Research Labs at 10mg per vial with greater than 99%+ HPLC-verified purity and batch-specific COA.
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Product Specifications
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- Sequence Length: 16 amino acids
- Origin: Mitochondrial genome (12S rRNA)
- Molecular Weight: Approximately 2174 Da
- Purity: >99%+ (HPLC verified)
- Form: Lyophilized powder
- Quantity: 10mg per vial
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MOTS-C Peptide Research Summary
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MOTS-C is a 16-amino acid peptide discovered in 2015, encoded within the mitochondrial genome, making it one of several mitochondrial-derived peptides (MDPs) identified as potential signaling molecules between mitochondria and the nuclear genome.
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Mechanism of Action Research
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Research has identified MOTS-C as an activator of the AMPK (AMP-activated protein kinase) signaling pathway, a central regulator of cellular energy homeostasis. Published studies have demonstrated that MOTS-C treatment in cell culture models leads to AMPK phosphorylation. In vitro studies have also demonstrated that MOTS-C can translocate to the nucleus under conditions of metabolic stress.
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All findings are from preclinical research. Researchers should consult primary sources for protocols.
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Certificate of Analysis (COA)
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Testing Laboratory: Testides (testides.com). Report Number: DBAV-MOTS-10-051226-02. Purity (HPLC-UV): 99.69%. Download Full COA (PDF)
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For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.
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