TB-500 10MG

TB-500 peptide: a synthetic version of a 43-amino acid region of Thymosin Beta-4 (TB4), a naturally occurring protein involved in cell migration and differentiation research. Available from Maple Research Labs with greater than 99%+ HPLC-verified purity and third-party COA testing.

• Sequence Region: Thymosin Beta-4 active fragment
• Molecular Weight: Approximately 4963 Da
• Purity: >99%+ (HPLC verified)
• Form: Lyophilized powder
• Quantity: 10mg per vial

TB-500 Peptide Research Summary

TB-500 is a synthetic peptide representing the active region of Thymosin Beta-4, a 43-amino acid protein expressed in virtually all mammalian cell types. It contains the key actin-binding domain (LKKTETQ) responsible for many of the observed biological activities in research settings. Research has focused on TB-500 interaction with globular actin (G-actin), which plays a central role in cytoskeletal dynamics.

Mechanism of Action Research

The primary molecular mechanism under investigation involves TB-500 ability to sequester G-actin monomers, thereby regulating actin cytoskeleton dynamics essential for cell migration. Published preclinical studies have examined TB-500 in the context of wound repair models, cardiac tissue research, and inflammatory response modulation in rodent and in vitro systems.

All published findings referenced here are based on animal models and in vitro systems. No therapeutic claims are made.

Certificate of Analysis (COA)

Testing Laboratory: Testides Analytical. Purity (HPLC-UV): 98.62%. Report: DBAV-TB500-10-051226. Download Full COA (PDF)

For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.

About this TB-500 reference material

TB-500 is supplied by Maple Research Labs as a lyophilised powder in a sealed vial under catalogue reference TB500-10MG. Every vial is drawn from a single production batch and is released only against a batch-specific certificate of analysis. The batch documented for this listing was tested by Testides Analytical, an independent third-party laboratory, and the report reference is shown in the specification above.

Analytical specification for this TB-500 batch

Identity and purity were determined by high-performance liquid chromatography with ultraviolet detection (HPLC-UV) and reported at 98.62%. The material is registered under CAS 77591-33-4, molecular formula C212H350N56O78S. HPLC-UV separates the target compound from related substances and process impurities and quantifies each as a percentage of total peak area, which is why the result is stated to two decimal places rather than as a rounded claim. Public registry data for CAS 77591-33-4 can be checked independently via PubChem.

What a batch-specific COA means

A batch-specific certificate describes the exact material in the vial being shipped, not a representative sample from an earlier production run. Where a supplier publishes a single document covering an entire product line, that certificate cannot describe the unit received. Maple Research Labs does not publish a TB-500 listing without a matching batch document, and the certificate for this batch is downloadable from this page.

Handling and storage

Supplied as a lyophilised powder. Store sealed vials away from light and moisture; refrigeration extends the shelf stability of the dry powder. Allow a chilled vial to reach ambient temperature before opening, to limit condensation on the stopper. Handle in a controlled laboratory environment using appropriate personal protective equipment, and record the batch reference against your own experimental documentation.

Availability and shipping

Orders ship from the United States. TB-500 is listed as a single vial, so a laboratory can verify the certificate and the material against its own analytical methods before committing to a larger order.

For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.

Third-party testing and traceability for TB-500

Testing for TB-500 is commissioned from Testides Analytical, a laboratory independent of both Maple Research Labs and the manufacturer. Independent testing matters because an in-house result is produced by the party with an interest in the outcome, and a third-party result is not. Each certificate states the analytical method used, the date of analysis and the batch identifier, so a result can be traced to a specific production run rather than to a product name in general.

Laboratories sourcing TB-500 for method development or comparative work generally need three things on file: a purity figure produced by a stated method, a batch identifier that matches the vial in hand, and a supplier willing to publish both before purchase rather than after. Those are the terms this listing is published on, and the certificate is available without an account or an enquiry.