MOTS-C 10MG

MOTS-C peptide: a mitochondrial-derived peptide encoded within the 12S rRNA gene of mitochondrial DNA. This research compound is available from Maple Research Labs at 10mg per vial with greater than 99%+ HPLC-verified purity and batch-specific COA.

Product Specifications

• Sequence Length: 16 amino acids
• Origin: Mitochondrial genome (12S rRNA)
• Molecular Weight: Approximately 2174 Da
• Purity: >99%+ (HPLC verified)
• Form: Lyophilized powder
• Quantity: 10mg per vial

MOTS-C Peptide Research Summary

MOTS-C is a 16-amino acid peptide discovered in 2015, encoded within the mitochondrial genome, making it one of several mitochondrial-derived peptides (MDPs) identified as potential signaling molecules between mitochondria and the nuclear genome.

Mechanism of Action Research

Research has identified MOTS-C as an activator of the AMPK (AMP-activated protein kinase) signaling pathway, a central regulator of cellular energy homeostasis. Published studies have demonstrated that MOTS-C treatment in cell culture models leads to AMPK phosphorylation. In vitro studies have also demonstrated that MOTS-C can translocate to the nucleus under conditions of metabolic stress.

All findings are from preclinical research. Researchers should consult primary sources for protocols.

Certificate of Analysis (COA)

Testing Laboratory: Testides (testides.com). Report Number: DBAV-MOTS-10-051226-02. Purity (HPLC-UV): 99.69%. Download Full COA (PDF)

For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.

About this MOTS-C reference material

MOTS-C is supplied by Maple Research Labs as a lyophilised powder in a sealed vial under catalogue reference MS10-MRL. Every vial is drawn from a single production batch and is released only against a batch-specific certificate of analysis. The batch documented for this listing was tested by Testides Analytical, an independent third-party laboratory, and the report reference is shown in the specification above.

Analytical specification for this MOTS-C batch

Identity and purity were determined by high-performance liquid chromatography with ultraviolet detection (HPLC-UV) and reported at 99.69%. The material is registered under CAS 1627580-64-6, molecular formula C78H123N23O24S2. HPLC-UV separates the target compound from related substances and process impurities and quantifies each as a percentage of total peak area, which is why the result is stated to two decimal places rather than as a rounded claim. Public registry data for CAS 1627580-64-6 can be checked independently via PubChem.

What a batch-specific COA means

A batch-specific certificate describes the exact material in the vial being shipped, not a representative sample from an earlier production run. Where a supplier publishes a single document covering an entire product line, that certificate cannot describe the unit received. Maple Research Labs does not publish a MOTS-C listing without a matching batch document, and the certificate for this batch is downloadable from this page.

Handling and storage

Supplied as a lyophilised powder. Store sealed vials away from light and moisture; refrigeration extends the shelf stability of the dry powder. Allow a chilled vial to reach ambient temperature before opening, to limit condensation on the stopper. Handle in a controlled laboratory environment using appropriate personal protective equipment, and record the batch reference against your own experimental documentation.

Availability and shipping

Orders ship from the United States. MOTS-C is listed as a single vial, so a laboratory can verify the certificate and the material against its own analytical methods before committing to a larger order.

For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.

Third-party testing and traceability for MOTS-C

Testing for MOTS-C is commissioned from Testides Analytical, a laboratory independent of both Maple Research Labs and the manufacturer. Independent testing matters because an in-house result is produced by the party with an interest in the outcome, and a third-party result is not. Each certificate states the analytical method used, the date of analysis and the batch identifier, so a result can be traced to a specific production run rather than to a product name in general.

Laboratories sourcing MOTS-C for method development or comparative work generally need three things on file: a purity figure produced by a stated method, a batch identifier that matches the vial in hand, and a supplier willing to publish both before purchase rather than after. Those are the terms this listing is published on, and the certificate is available without an account or an enquiry.