Product Specifications
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- Compound: Tirzepatide (Dual GIP/GLP-1 Receptor Agonist)
- CAS Number: 2023788-19-2
- Molecular Weight: 4813.45 g/mol
- Sequence: 39 amino acid linear peptide with C-20 fatty diacid modification
- Purity: >99%+ (HPLC verified)
- Form: Lyophilized powder
- Quantity: 10mg per vial
- Third-Party Testing: Testides Analytical (independent third-party lab)
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Mechanism of Action
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Tirzepatide is a synthetic 39-amino acid peptide engineered as a dual agonist targeting both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor. In-vitro receptor binding assays demonstrate that tirzepatide exhibits approximately 5-fold selectivity for the GIP receptor relative to GLP-1. The peptide incorporates a C-20 fatty diacid moiety that facilitates albumin binding, extending its pharmacokinetic half-life in preclinical models.
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Research Applications
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Tirzepatide has been investigated across multiple preclinical research domains. In-vitro studies have demonstrated its effects on incretin signaling pathways, including cAMP accumulation in GIP and GLP-1 receptor-expressing cell lines. In animal models, research has examined its influence on pancreatic islet cell function and central metabolic signaling pathways versus single-receptor agonism.
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How Tirzepatide Compares to Other Research Peptides
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Tirzepatide belongs to the incretin-targeting peptide family alongside semaglutide (selective GLP-1 agonist) and retatrutide (triple GIP/GLP-1/glucagon agonist). While semaglutide activates only the GLP-1 receptor, tirzepatide dual mechanism engages both GIP and GLP-1 pathways.
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Storage and Handling
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Store lyophilized tirzepatide at -20C for long-term stability. Reconstituted solution should be stored at 2-8C and used within 30 days. Avoid repeated freeze-thaw cycles.
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Shipping from the USA
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All tirzepatide orders ship same-day from our US facility with temperature-controlled packaging. Free shipping on orders over $200.
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Certificate of Analysis (COA)
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Testing Laboratory: Testides Analytical. Purity (HPLC-UV): 99.88%. Report: DBAV-TIRZ-10-052926. Download Full COA (PDF)
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For research purposes only. Not for human consumption. Not for diagnostic or therapeutic use.





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